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Analyze numerous isomeric lipid species - MOBILion Systems | ASMS 2022

MOBILion Eye

Flexibility of HRIM-MS Analysis for Targeted Lipid Profiling: Choose Your Own Adventure!

Author(s)

Kelly Wormwood Moser PhD - MOBILion Systems, Inc

Abstract

Lipids are challenging to analyze due to the presence of numerous isomeric species, many of which cannot be distinguished via traditional LC-MS approaches. The introduction of HRIM provides the analytical separation power to begin to unravel very structurally similar lipid species, including isomers. Flow injection and liquid chromatography are complementary front-end sample introduction methods for HRIM-MS that provide high throughput analysis and deeper sample characterization, respectively.

Customer Intro
Problem
Solution
Conclusions
Abstract
  • FIA-HRIM-MS provides high-throughput (≤2 min)analysis of the most abundant lipids in a ganglioside extract.
  • Coupling HRIM-MS with LC enables deeper characterization of the sample by reducing ion suppression.
  • Both workflows utilize HRIM for highly reproducible gas phase separation.
Results
Analyze numerous isomeric lipid species - MOBILion Systems | ASMS 2022

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