Posters

Resolution of Isomers via High Resolution Ion Mobility (HRIM) Mass Spectrometry

Resolution of Isomers via High Resolution Ion Mobility (HRIM) Mass Spectrometry Incorporating Structures for Lossless Ion Manipulation

Author(s)

Alison Reardon - Vanderbilt

Abstract

Customer Intro

Problem

Solution

Conclusions

Abstract

These results suggest that simultaneously scanning the wave speed and the wave amplitude should allow the highest Rp values to be achieved across a range of m/z
The CCS difference percentage between HRIM calculated and database is analyte dependent
For the targeted separations of several biochemical isomers (peptides, lipids, and carbohydrates), the HRIM platform achieved near to full-baseline resolutions for the corresponding isomeric mixtures

Results