Posters

Characterization of Polysorbate, Polyethers, and Surfactants Compounds - Agilent Technologies | ASMS 2022

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Comparison of Drift-tube Ion Mobility and Structures for Lossless Ion Manipulations (SLIM) for Characterization of Polysorbate, Polyethers, and Surfactants Compounds

Author(s)

David Weil PhD - Agilent Technologies

Abstract

To assess the technical feasibility and analytical capabilities of using a Drift-Tube based Ion Mobility Mass Spectrometry (IM-MS) system with high resolution demultiplexing and the Structures for Lossless Ion Manipulations (SLIM) based High Resolution Ion Mobility device coupled to a 6546 LC/Q-TOF for separation of structurally similar isobaric and isomeric oligomeric Polyether and Polysorbates surfactants.

Customer Intro
Problem
Solution
Conclusions
Abstract
  • Full Spectrum ion mobility separations provides significant advantages for analysis of complex polymer samples
  • Ability to Separate Coeluting Compounds
  • Ability to Observe Trend Lines in Oligomeric Compounds
  • Ability to Identify Minor Components in Presence of Complex Polymer Matrix
  • Ability to improve identifications based on Collision Cross Section conversion
  • Existing Software Solutions Enable 4-D Feature Finding & Processing
Results

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