Posters
Comprehensive biotherapeutic analysis on a single MOBIE platform - MOBILion Systems | ASMS 2022
Characterization of Biotherapeutics with High-Resolution Ion Mobility- Mass Spectrometry
Author(s)
Steven Broome - MOBILion Systems, Inc
Abstract
Ensuring the efficacy and safety of biotherapeutics is essential and often requires multiple workflows (intact, subunit, peptide, and released glycan) that rely on LC-MS for full characterization. Here we demonstrate the use of an LC-HRIM-MS system combined with Protein Metrics Byos for HRIM data processing module as a single platform solution for in-depth biotherapeutic characterization for all workflows.
Customer Intro
Problem
Solution
Conclusions
Abstract
- Comprehensive biotherapeutic analysis was performed on a single platform including, intact, subunit, peptide mapping, and released glycan LC-HRIM-MS workflows.
- Incorporation of MOBIE HRIM into traditional characterization workflows increases confidence in results by measuring unique and consistent arrival times.
- The Protein Metrics Byos for HRIM workflows provide an efficient data processing solution for all characterization workflows.
Results
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