Introducing SLIM Technology

Developed in the labs of Dr. Richard D. Smith at Pacific Northwest National Laboratory, SLIM (Structures for Lossless Ion Manipulation) separations technology provides unprecedented capability to separate and detect clinically relevant molecules that are indistinguishable by current instruments.

Meet The Inventor

Dr. Richard D. Smith is one of the most prolific scientists in advanced analytical methods for biological research; consistently inventing disruptive technology for over two decades. Recently, he led the development of the novel SLIM for high-throughput sample processing, reactions, and separations with a world renowned team of scientists at Pacific Northwest National Laboratory.

SLIM Technology Advantage

SLIM enables researchers to detect and analyze molecules indicative of disease like never before, outperforming the most advanced LC-MS (Liquid Chromatography–Mass Spectrometry) instruments. Not only is SLIM capable of detecting minute traces of many disease specific biomolecules, it can complete the analysis in a reasonable amount of time and within a compact footprint.


High Resolution

SLIM allows us to explore biologic systems well beyond genomics with 10x more sensitivity; molecules indistinguishable by current instruments are unambiguously identified with SLIM


High Throughput

SLIM provides throughput of minutes not hours, enabling population scale studies in a reasonable amount of time; allowing scientists, researchers, and clinicians to move faster


Compact Footprint

SLIM can move ions around a limitless number of corners providing 10x ion path length compared to current technologies. This means it can fit in a small footprint and act as a point of care clinical diagnostic tool

How SLIM Works

SLIM separations technology applies electric fields to electrodes on conventional parallel printed circuit board surfaces creating ion conduits that can separate and move ions losslessly. Lossless Ion Manipulation is a revolutionary technology that will enable robust biological analysis from minute sample quantities.