Targeted Lipidomics
Resolve Structural Details Like Never Before
Lipids represent the most diverse set of molecules in human biology, with extremely heterogeneous underlying chemistry. They play essential roles in biological processes and are indicated in the diagnosis and progression of many neurodegenerative diseases.
The Problem
Unravel the complexity of Lipid Analysis
Because of the high complexity of lipidomes, and the vast number of isomers present, separation, detection, and quantitation of all the lipid species within a lipidome can be extremely difficult and time consuming.
Precise determination of underlying isobaric and isomeric species comprising lipidomes is hindered by structural details that cannot be resolved by traditional workflows based on liquid chromatography.
Our Solution
Identification of isobaric and isomeric species is hindered by structural details that cannot be resolved by traditional workflows.
The MOBIE® platform resolves more lipid isomers 10x faster with the highest reproducibility available today.
Benefits of HRIM
Incorporating MOBIE into lipid analysis workflows allows for the rapid, discrimination of isomeric and isobaric species indistinguishable via MS alone.
- Resolution of more lipid isomers, including cis/trans bonds and double bonds
- Exceptional throughput, with 2-minute analysis of the most abundant lipids
- Collision cross section reproducibility of ≤ 0.25%
HRIM analysis on the MOBIE platform baseline resolves lipid isomers that traditional LC-MS cannot.
Customer Success Story
Resolving Complex Lipid Structures
Kim Ekroos PhD - Lipidomics Consulting Inc.
MOBIE achieves separation of molecules with close structural heterogeneity without LC
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