When we started on the path to developing our first high resolution ion mobility product in 2018, there was no way that we could have envisaged having to launch it to a virtual audience who were unable to get up close and personal to see and experience the game-changing capabilities for themselves.
However, patience is a virtue, and we were thrilled to finally introduce MOBIE® to the industry and meet everyone at the first in-person ASMS event since 2019 and celebrate the 69th year of the show with all of our colleagues in the mass spec industry.
While we have been lucky enough to attend a few face-to-face trade shows in 2021 (restrictions permitting), the whole team here at MOBILion Systems had really been building up to ASMS – not least because it was right here in our backyard in Philadelphia!
Here’s a roundup of our exciting week at the show…
Optimizing of data pre-processing parameters on the first commercial SLIM-based HRIM-MS platform for targeted and untargeted analysis workflows.
Analyses of highly similar glycopeptides via high resolution ion mobility to rapidly determine microheterogeneity for both N- and O-linked glycopeptides
Liquid-Chromatography High-Resolution Ion Mobility-Mass Spectrometry (LC-HRIM-MS) analysis and Protein Metrics HRIM workflows allow for high throughput characterization of protein glycosylation.
Characterizing gangliosides using high-throughput LC-HRIM-MS platform with identification of well-resolved potential isomeric species.
First report of a SLIM-based spatial ion mobility analyzer capable of transmitting a continuous ion beam
Here we demonstrate the capabilities of HRIM-MS to distinguish potentially disease-relevant isoforms of recombinant tau.
Implementation of 3D printed protypes in high vacuum instrumentation, leveraging acetone vapor smoothing to eliminate virtual leaks.
First report of quantitative performance metrics measured across multiple systems for a commercial SLIM-based HRIM device.
Automated pressure control system significantly improves the performance of SLIM for high resolution ion mobility separations
Native protein analysis enabled by Ion Mobility-MS—demonstrate the efficacy of a new ALS drug candidate.
Initial developments towards a SLIM IMS device having both oscillating (traveling wave) and constant drift field regions.
SLIM-based instrument was used to yield high-precision, relative mobilities. We propose a framework for standardizing relative mobilities.
High resolution SLIM TWIM resolves numerous isomeric lipids from biological lipid fractions over conventional resolution IM.
Characterization and CCS measurements of cardiolipin and ceramide phosphoethanolamine lipids using a new prototype high-resolution SLIM-based ion mobility-mass spectrometer.
Investigation of calibration strategies and calibrant sets for traveling wave ion mobility measurements of lipids on a SLIM device.
Thank you to all of the players for making the first #wheresmobie challenge such a success! We had over 100 participants with a combined total of 665 challenge submissions. We can’t wait to see what next year brings, so stay tuned for the next #wheresmobie challenge.