Application Notes

Merck - Drug Development: Cyclic Peptides

Author(s)

Komal Kedia

Abstract

To enhance Merck’s drug development efforts by providing a faster time to answer vs. alternative LC approaches with greater resolving power for the identification of soft spots in cyclic peptides, providing greater confidence, increased accuracy, higher efficiency, simplified workflow and reduced overall cost.

Customer Intro

Problem

Solution

Merck utilized the MOBIE system to more accurately characterize cyclic peptide soft spots with a 200% higher resolving power than alternative ion mobility methods, and demonstrated a 72% faster time to answer than alternative LC/MS approaches.

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