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Noncovalent Copper Complexation to Differentiate Drug Enantiomers by Conventional and High-Resolution Ion Mobility-Mass Spectrometry

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Noncovalent Copper Complexation to Differentiate Drug Enantiomers by Conventional and High-Resolution Ion Mobility-Mass Spectrometry

Author(s)

Benjamin K. Blakley, Emanuel Zlibut, Allison R. Reardon, Jody C. May, John A. McLean

Abstract

Due to chiral specificity on drug pharmacology, there is no table pharmaceutical demand for high throughput methods to differentiate and quantify enantiomeric excess in chiral drugs.

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Noncovalent Copper Complexation to Differentiate Drug Enantiomers by Conventional and High-Resolution Ion Mobility-Mass Spectrometry

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