Resources

Characterization of Diabetes Biomarkers using High-Resolution Ion Mobility – Mass Spectrometry

Diabetes Biomarkers, High-Resolution Ion Mobility, Mass Spectrometry, University of Florida, MOBILion Systems, Proinsulin, C-peptide, Insulin, Glycated Hemoglobin A1c (HbA1c), High-Resolution Mobility Patterns, Isomeric Glycated Peptides, Metabolic Syndrome Markers, HRIM Advantages,

Characterization of LNP Impurities and Degradation Products Using High-Resolution Ion Mobility (HRIM) Mass Spectrometry

MOBIE HRIM Platform, LNP impurities, degradation products, lipid nanoparticle analysis, LC-HRIM-MS workflow, resolving powers, isomeric species, isobaric species, HRIM technology, lipid component identification, LNP safety, therapeutic product analysis.

Characterizing the Molecular Composition of Polysorbates by High Resolution Ion Mobility-Mass Spectrometry (HRIM-HRMS)

Polysorbates, molecular composition, High-Resolution Ion Mobility-Mass Spectrometry, HRIM-HRMS, isomer separation, liquid chromatography, DTIM-MS, TWSLIM-HRIM, bioavailability, structural analysis, surfactants, mass spectrometry, analytical techniques

Establishing an LC-HRIM-MS Workflow for Untargeted Lipidomic Analyses

LC-HRIM-MS Workflow, Untargeted Lipidomic Analysis, SLIM-Based Technology, MOBIE Platform, High-Resolution Ion Mobility, CCS Database, Authentic Reference Standards, Lipid Separation, Identification, Quantitation, Lipostar Workflow, Next-Generation Ion Mobility Instrumentation, Structural Specificity, Complex Lipid Mixtures, NIST SRM 1950, Agilent QTOF, Agilent LC System, Lipid Extracts, Isomeric Species, Multidimensional Separations

High Resolution Ion Mobility-Mass Spectrometry (HRIM-MS) for Rapid Resolution of Peptides Containing Deamidation and Isoaspartic Acid

High Resolution Ion Mobility-Mass Spectrometry (HRIM-MS), Peptides, Deamidation, Isoaspartic Acid, UHPLC-MS, Chemical modifications, Therapeutic proteins, Isotopic envelopes, Chromatographic separation, Synthetic peptides, Flow injection analysis (FIA), Mass spectrometry, Arrival time distribution, Peak-to-peak resolution (Rpp), Observed species, Method optimization, Adducts, Sodium adducts, Complementary separation, Principal Component Analysis (PCA), Physical properties, N-terminal residue.

Improved Separation of Lipid Extracts Using High Resolution Ion Mobility Incorporating Structures for Lossless Ion Manipulation in LC-HRIM-HRMS

Improved Separation, Lipid Extracts, High Resolution Ion Mobility, Lossless Ion Manipulation, LC-HRIM-HRMS, MOBILion Systems, Lipid Isomers, Lipid Trendline Analysis, LC-HRMS, HRIM Advantages, Lipidomics, Calibration Techniques.

Integration of a SLIM-based High Resolution Ion Mobility Prototype with an Orbitrap Mass Spectrometer

SLIM-Based High Resolution Ion Mobility, Orbitrap Mass Spectrometer, Signal Enhancement, Sensitivity, Low-Abundance Analytes, SLIM-Orbitrap Platform, High-Speed Pre-Fractionator, HRIM Separation, Duty Cycle, Signal Gain Factors, Proteomics Research, Ion Mobility Technology, Orbitrap Mass Analysis

MOBIE – A Flexible Structures for Lossless Ion Manipulation (SLIM) Based High-Resolution Ion Mobility Platform

Native HRIM MS Eliminates Chemical Noise and Enables Quaternary Structure Analysis of ALS associated SOD1 Proteoforms

Native HRIM-MS, Chemical Noise, Quaternary Structure Analysis, ALS-associated SOD1 Proteoforms, Ion Mobility Mass Spectrometry, Native MS, ESI Sources, SLIM-QTOF System, Protein Structure Analysis, Northeastern University, Harvard Medical School, Nano Electrospray, Micro Electrospray, High-Flow Electrospray

Noncovalent Copper Complexation to Differentiate Drug Enantiomers by Conventional and High-Resolution Ion Mobility-Mass Spectrometry

Noncovalent Copper Complexation, Drug Enantiomers, Ion Mobility-Mass Spectrometry, MOBILion Systems, Vanderbilt University, Chiral Selectors, Racemic Drugs, High-Resolution Ion Mobility, Copper-Histidine Complexes, Enantiomeric Excess, Mass Spectrometry

PFAS Dark Matter and Slippery Cannabis: Disparate Problems with a Similar Path to a Solution

PFAS, cannabinoids, LC, HRIM, QTOF, collision cross section, ion mobility, mass spectrometry, sample characterization, compound identification, complex mixtures.

Pushing the Boundaries of Multidimensional Separations: Coupling 2D Chromatography with High-Resolution Structures for Lossless Ion Manipulations (SLIM) IM-MS

Multidimensional separations, 2D chromatography, High-Resolution Structures for Lossless Ion Manipulations (SLIM) IM-MS, Ion mobility spectrometry (IMS), LC-MS assays, Anabolic steroids, Steroid metabolites, Collision cross section (CCS), Isomers/isobars differentiation, Human urine analysis, Developmental disorders, Sports doping, SLIM-based high-resolution IM, Complex biological samples, Analytical chemistry, Steroid profiling